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Xtandi
What is Xtandi?
Xtandi is an anti-androgen. It works in the body by preventing the actions of androgens (male hormones).
Xtandi is used to treat prostate cancer
Xtandi is sometimes used when the cancer no longer responds to treatment, but has not spread to other parts of the body.
Xtandi is also used when the cancer has responded to treatment and has spread to other parts of the body (metastatic).
Warnings
Although not for use by women, Xtandi can cause birth defects if the mother or the father is taking this medicine. Use a condom and one other form of birth control to prevent pregnancy during your treatment, and for at least 3 months after your treatment ends.
Xtandi may cause side effects on your spinal cord. Stop taking this medicine and call your doctor at once if you have severe low back pain, trouble walking or standing up, pain or weakness in your lower body, severe and worsening numbness or tingling, or sudden loss of bladder or bowel control.
How should I take Xtandi?
Take Xtandi exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
You may take Xtandi with or without food. Take the medicine at the same time each day.
You may need to take two 80mg tablets or four 40mg tablets or capsules at the same time once a day to get a full dose.
Swallow the Xtandi tablet or capsule whole. Do not break, chew, or crush a tablet. Do do not chew, open, or dissolve a capsule.
Prostate cancer is sometimes treated with a combination of drugs. Use all medications as directed by your doctor. Do not change your doses or medication schedule without your doctor’s advice.
Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.
What happens if I miss a dose?
Take the missed dose if you remember it later in the day. Skip the missed dose if it is almost time for your next day’s dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention. An overdose could cause you to have a seizure.
What to avoid
Enzalutamide can increase your risk of seizure. Avoid any activity that could be dangerous if you have a seizure or lose consciousness.
Avoid driving or hazardous activity until you know how Xtandi will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Even without dizziness, taking Xtandi could increase your risk of falls or bone fractures. Avoid activities or situations that may lead to injury or falls.
Xtandi side effects
Stop taking Xtandi and get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Xtandi may cause side effects on your spinal cord. Stop taking this medicine and call your doctor at once if you have:
- dizziness, spinning sensation;
- a seizure (black-out or convulsions);
- confusion, thinking problems, severe headache, vision problems;
- weakness, loss of consciousness;
- red or pink urine;
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common Xtandi side effects may include:
- feeling weak or tired;
- constipation, diarrhea;
- loss of appetite;
- flushing (redness, hot feeling);
- back pain, joint pain; or
- high blood pressure.
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