MY BIG PHARMACY NIG LTD IS THE FOREMOST SUPPLIER OF OVITRELLE 250 MCG/0.5 ml IN NIGERIA.

Ovitrelle

Therapeutic indication

Ovitrelle is indicated in the treatment of:

• women undergoing superovulation prior to assisted reproductive techniques such as in vitro fertilisation (IVF): Ovitrelle is administered to trigger final follicular maturation and luteinisation after stimulation of follicular growth;
• anovulatory or oligo-ovulatory women: Ovitrelle is administered to trigger ovulation and luteinisation in anovulatory or oligo-ovulatory patients after stimulation of follicular growth.

What is Ovitrelle?

Ovitrelle is a medicine that contains the active substance choriogonadotropin alfa. It is available as a powder and solvent to be made up into a solution for injection and as a solution in a prefilled syringe or prefilled pen.

What is Ovitrelle used for?

Ovitrelle is used in women who have received treatment to stimulate their ovaries, to trigger ovulation (the release of eggs by the ovaries) and the development of a special structure on the ovary (the corpus luteum) that helps pregnancy.

It can be used in women who are undergoing fertility treatment (such as in vitro fertilisation), and in women who are anovulatory (do not produce eggs) or oligo-ovulatory (rarely produce eggs).

Ovitrelle can only be obtained with a prescription.

How is Ovitrelle used?

Treatment with Ovitrelle should be carried out under the supervision of a doctor who has experience in the treatment of fertility problems.

Ovitrelle is given by injection under the skin. A dose of 250 micrograms is given 24 to 48 hours after the ovaries have produced follicles that are mature enough (eggs ready for ovulation). In women undergoing fertility treatment, this is generally 24 to 48 hours after stopping treatment to stimulate the ovaries (such as a follicle stimulating hormone [FSH] or human menopausal gonadotrophin [hMG] preparation). The patient or their partner may carry out the injection if they have been trained and have access to expert advice.

How does Ovitrelle work?

The active substance in Ovitrelle, choriogonadotropin alfa, is a copy of the natural hormone human chorionic gonadotropin (hCG), also known as the ‘pregnancy’ hormone, which helps to maintain pregnancy. Because of its similarity to luteinising hormone (LH), Ovitrelle is also used to trigger ovulation.

The choriogonadotropin alfa in Ovitrelle is produced by a method known as ‘recombinant DNA technology’: it is made by a cell that has received a gene (DNA), which makes the cell able to produce it.

Why has Ovitrelle been approved?

The CHMP decided that Ovitrelle’s benefits are greater than its risks and recommended that it be given marketing authorisation.

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