INTRODUCTIONS:
The active ingredient Leucostim is Filgrastim, a human granulocyte-stimulating factor produced by recombinant DNA technology. The drug has a stimulating effect on the production, maturation and activation of neutrophils to increase their migration, cytotoxicity.
1. What is Leucostim?
Leucostim drug has the main ingredient is Filgrastim, a human granulocyte colony-stimulating factor produced by recombinant DNA technology with activity similar to the endogenous human granulocyte-stimulating factor. Leucostim helps regulate the production and mobilization of neutrophils from the bone marrow. The drug stimulates the activation, proliferation and differentiation of neutrophil progenitor cells. In some cases of chronic neutropenia, treatment with Leucostim also increased the production of eosinophils and basophils. When treatment was discontinued, circulating neutrophils decreased by 50% within 1-2 days and returned to normal within 1-7 days.
2. Uses of Leucostim
Filgrastim is indicated to shorten the duration and complications of leukopenia in patients receiving cytotoxic chemotherapy, myelosuppressive therapy patients preparing for bone marrow transplantation.
Long-term use of Filgrastim increases the number of neutrophils, reduces the frequency and duration of infectious episodes in patients with congenital neutropenia, cyclic neutropenia, and leukopenia. idiopathic, drug-induced leukopenia, or non-myeloid cancer.
Long-term use of Filgrastim increases the number of neutrophils, reduces the frequency and duration of infectious episodes in patients with congenital neutropenia, cyclic neutropenia, and leukopenia. idiopathic, drug-induced leukopenia, or non-myeloid cancer.
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