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Human chorionic gonadotropin (HCG)
What is HCG?
Human chorionic gonadotropin (HCG) is a hormone that supports the normal development of an egg in a woman’s ovary, and stimulates the release of the egg during ovulation.
HCG is used to cause ovulation and to treat infertility in women, and to increase sperm count in men. HCG is also used in young boys when their testicles have not dropped down into the scrotum normally. This can be caused by a pituitary gland disorder.
HCG may also be used for other purposes not listed.
Warnings
HCG is given as an injection under the skin or into a muscle. If you use HCG at home, your doctor, nurse, or pharmacist will give you specific instructions on how and where to inject this medicine. Do not self-inject HCG if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
HCG can place you at higher risk for a blood clot. Call your doctor at once if you have any of these signs of a blood clot: pain, warmth, redness, numbness, or tingling in your arm or leg; confusion, extreme dizziness, or severe headache.
Some women using this medicine have developed a condition called ovarian hyperstimulation syndrome (OHSS), especially after the first treatment cycle. OHSS can be a life-threatening condition. Call your doctor right away if you have any symptoms of OHSS: severe pelvic pain, swelling of the hands or legs, stomach pain and swelling, shortness of breath, weight gain, diarrhea, nausea or vomiting, or if you are urinating less than normal.
HCG can cause early puberty in young boys. Call your doctor if a boy using this medicine shows early signs of puberty, such as a deepened voice, pubic hair growth, and increased acne or sweating.
Using HCG can increase your chances of having a multiple pregnancy (twins, triplets, quadruplets, etc). A multiple pregnancy is a high-risk pregnancy for the mother and for the babies. Follow your doctor’s instructions about any special care you may need during your pregnancy.
Although HCG can help you become pregnant, it should not be used during pregnancy. Tell your doctor right away if you become pregnant during treatment.
HCG has no known effect on appetite, hunger, fat loss, or fat distribution. It is not approved by the FDA as a weight loss medication or for the treatment of obesity.
What happens if I miss a dose?
Contact your doctor if you miss a dose of HCG.
What happens if I overdose?
Seek emergency medical attention if you think you have used too much of this medicine. An overdose of HCG is not expected to produce life-threatening symptoms.
HCG side effects
Stop using HCG and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.Call your doctor at once if you have any of these signs of a blood clot: pain, warmth, redness, numbness, or tingling in your arm or leg; confusion, extreme dizziness, or severe headache.
Some women using this medicine have developed a condition called ovarian hyperstimulation syndrome (OHSS), especially after the first treatment cycle. OHSS can be a life-threatening condition. Call your doctor right away if you have any of the following symptoms of OHSS:
- severe pelvic pain;
- swelling of the hands or legs;
- stomach pain and swelling;
- shortness of breath;
- weight gain;
- diarrhea;
- nausea or vomiting; or
- urinating less than normal.
HCG can cause early puberty in young boys. Call your doctor if a boy using this medicine shows early signs of puberty, such as a deepened voice, pubic hair growth, and increased acne or sweating.
Less serious side effects fomr HCG may include:
- headache;
- feeling restless or irritable;
- mild swelling or water weight gain;
- depression;
- feeling tired;
- breast tenderness or swelling; or
- pain, swelling, or irritation where the injection is given.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect HCG?
There may be other drugs that can interact with HCG. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
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