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What is Duromine used for​​​?

Duromine (Phentermine) is an anorectic agent (an agent that suppresses appetite). It is for people with overweight and weight-related complications or obesity. It is meant to be used as a short-term adjunct in a comprehensive regimen of weight reduction, which includes diet and exercise.

How much weight can I lose with Duromine (Phentermine)?

Duromine (Phentermine) can support meaningful weight loss by decreasing your hunger or making you feel full longer. The expected average weight loss with phentermine use is 5-10% of your initial body weight over 12 weeks.

Dosage and How to Use​

• Duromine comes in capsule form, to be taken by mouth.
• Swallow the capsules whole with plenty of water. Do not chew or open the capsules.
• The best time to take Duromine is first thing in the morning (before breakfast or 1 to 2 hours after breakfast), as it can cause sleeplessness if taken at night. Taking it at the same time each day will have the best effect. It will also help you remember when to take it.
• It is important that you take the dose the doctor has recommended for you. Taking more than the recommended dose will increase the side effects you experience and may not increase the effect on weight loss.

What to do if I missed a dose?

If you forget to take your Duromine dose at breakfast, take it no later than lunchtime. Alternatively, skip the dose you missed and take your next dose at the normal time on the next day. If you take Duromine any later than lunchtime you may have trouble sleeping at night.

Never take a double dose to make up for a dose you have missed.

What are the possible side effects of Duromine (Phentermine)?​

Common side effects include:

• Dry mouth and unpleasant taste
• Restlessness
• Difficulty sleeping: Take Duromine first thing in the morning, reduce caffeine intake or consider prescription-grade melatonin (Circadin)
• Palpitations
• Increased blood pressure

What precautions should I take?

Inform your healthcare professional if:

• You are allergic to this medication or any of the other ingredients of this medication
• You are pregnant, planning to become pregnant, or breastfeeding – inform your doctor immediately if you become pregnant while on phentermine.
• You are taking any other medications, including supplements, traditional medications and herbal remedies
• You have a history of or current medical conditions such as pulmonary artery hypertension, existing heart valve abnormalities or heart murmurs, moderate to severe arterial hypertension, cerebrovascular disease, severe cardiac disease, known hypersensitivity to sympathomimetic drugs, hyperthyroidism, agitated states or a history of psychiatric illness including anorexia nervosa and depression, glaucoma, history of drug/alcohol abuse.

Do not drive a car or operate heavy machinery until you know how Duromine affects you. Duromine can slow your thinking and motor skills and also may affect your vision.

What other medications and foods should I avoid when taking Duromine?

Some medications including antibiotics and antifungals may affect how the medication works or be affected by the medication. Please inform your healthcare professional about all the medicines and supplements you take, especially the following medicines:

• Monoamine oxidase inhibitors (MAOIs)—usually used to treat depression
• Adrenergic neuron blocking drugs—these are usually taken to treat high blood pressure or psychotic symptoms
• Selective serotonin reuptake inhibitors (SSRIs)—used to treat depression and anxiety

Please inform your healthcare professionals that you are taking Duromine if you are seeing them for other medical conditions.

Do not drink alcohol while taking phentermine.

Handling and storage

• ​Keep your medicines in the original container or packaging, tightly closed or sealed in a cool and dry place, away from direct sunlight.
• Keep the medicine out of reach of children.
• Throw away all expired medicines

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